Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837553 | 0.84 | XIAP (0.45) | XIAPCCKBRNPY1R | |
| SCHEMBL7848691 | 0.80 | XIAP (0.46) | XIAPCCKBRNPY1R | |
| SCHEMBL7836160 | 0.79 | AADAT (0.46) | TP53MAPTKMT2AMEN1ALPL | |
| SCHEMBL2847250 | 0.71 | NPY1R (0.49) | XIAPKMT2ANPY1RL3MBTL1 | |
| SCHEMBL7835962 | 0.70 | GAA (0.43) | POLB | |
| SCHEMBL7417336 | 0.69 | NPY1R (0.51) | XIAPCCKBRNPY1RL3MBTL1 | |
| SCHEMBL2840169 | 0.69 | NPY1R (0.47) | XIAPKMT2ACCKBRNPY1RL3MBTL1 | |
| SCHEMBL5132571 | 0.69 | NPY1R (0.59) | XIAPKMT2ACCKBRNPY1RL3MBTL1 | |
| SCHEMBL7416762 | 0.69 | NPY1R (0.59) | XIAPKMT2ACCKBRNPY1RL3MBTL1 | |
| SCHEMBL7421160 | 0.68 | SCN9A (0.48) | CCKBRNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802922-B1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0802922-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995023810-A1 | NOVEL AMINO ACID DERIVATIVES, METHOD OF PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM KG (DE) | 1995-09-08 | — | — | WO | disclosed |