Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829574 | 0.81 | LMNA (0.36) | EGFRKDRNPC1MAPT | |
| SCHEMBL7839823 | 0.79 | EGFR (0.36) | EGFRDRD1KDRTRPA1 | |
| SCHEMBL7840014 | 0.76 | PDPK1 (0.43) | NPC1MAPT | |
| SCHEMBL8813155 | 0.75 | NPC1 (0.32) | EGFRNPC1 | |
| SCHEMBL7821542 | 0.71 | NPC1 (0.43) | EGFRDRD1NPC1MAPT | |
| SCHEMBL7833358 | 0.71 | EIF2AK2 (0.43) | EGFRKDR | |
| SCHEMBL3781844 | 0.66 | AADAT (0.60) | — | |
| SCHEMBL7348448 | 0.66 | MAPT (0.42) | NPC1MAPT | |
| SCHEMBL7347464 | 0.64 | TOP1 (0.49) | NPC1 | |
| SCHEMBL30446689 | 0.64 | TDP1 (0.45) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802914-B1 | ARYL- AND HETEROARYL- PURINE AND PYRIDOPYRIMIDINE DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-06-06 | — | — | EP | claimed |