Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | CTSG | P08311 | 5/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.45 |
| ▸ | CMA1 | P23946 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835765 | 0.80 | MEN1 (0.49) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7837405 | 0.77 | MEN1 (0.47) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7834666 | 0.77 | SIGMAR1 (0.41) | PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL7836334 | 0.76 | NPC1 (0.49) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7837709 | 0.76 | EPHX2 (0.47) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7825860 | 0.75 | PRSS1 (0.58) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7837208 | 0.74 | CTSG (0.47) | PRSS1CTSGCTRB1CMA1EPHX2 | |
| SCHEMBL7825623 | 0.74 | CTSG (0.61) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL507273 | 0.74 | EPHX2 (0.55) | NPC1RAB9APRSS1CTSGCTRB1 | |
| SCHEMBL7835566 | 0.73 | PRSS1 (0.45) | NPC1RAB9APRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |