Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455259 | 0.90 | HTR2C (0.39) | HTR2C | |
| SCHEMBL529103 | 0.80 | PTGDR2 (0.36) | PTGS2PTGDR2HTR1AHTR7PDCD1 | |
| SCHEMBL9644212 | 0.80 | PTGDR2 (0.36) | PTGS2PTGDR2HTR1AHTR7PDCD1 | |
| SCHEMBL432692 | 0.78 | PTGS2 (0.37) | PTGS2HTR2CPTGDR2HTR1AHTR7 | |
| SCHEMBL435126 | 0.78 | CEL (0.40) | PTGS2PTGDR2HTR1AHTR7PDCD1 | |
| SCHEMBL3690036 | 0.78 | PTGDR2 (0.38) | PTGS2PTGDR2PDCD1CD274CEL | |
| SCHEMBL8190571 | 0.78 | MEN1 (0.37) | PTGS2HTR2CPTGDR2HTR1AHTR7 | |
| SCHEMBL1819043 | 0.78 | HTR1A (0.36) | PTGS2PTGDR2HTR1AHTR7PDCD1 | |
| SCHEMBL23071363 | 0.76 | CEL (0.34) | PTGS2PTGDR2HTR1AHTR7PDCD1 | |
| SCHEMBL1816231 | 0.74 | SIGMAR1 (0.34) | HTR2CCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828901-B2 | Preparation of a solid catalyst system | BOREALIS AG (AT) | 2014-09-09 | — | — | US | disclosed |
| US-20130245212-A1 | PREPARATION OF A SOLID CATALYST SYSTEM | BOREALIS AG (AT) | 2013-09-19 | — | — | US | disclosed |
| EP-0959882-A4 | N-LINKED UREAS AND CARBAMATES OF HETEROCYCLIC THIOESTERS | HAMILTON GREGORY S (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0959882-A1 | N-LINKED UREAS AND CARBAMATES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998029117-A1 | N-LINKED UREAS AND CARBAMATES OF HETEROCYCLIC THIOESTERS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-07-09 | — | — | WO | disclosed |
| EP-0360085-A2 | Offset printing and offset dyestuffs | BAYER AG (DE) | 1990-03-28 | — | — | EP | disclosed |