Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1602718 | 0.80 | ALDH1A1 (0.56) | LOXL2CHRM5CHKACYP1A2CYP3A4 | |
| SCHEMBL27947483 | 0.80 | SMN1; SMN2 (0.50) | LOXL2CHRM5CHKACYP1A2CYP3A4 | |
| SCHEMBL30093206 | 0.78 | KDM4E (0.53) | LOXL2CHRM5CHKACYP1A2CYP3A4 | |
| SCHEMBL22928691 | 0.76 | CYP1A2 (0.44) | LOXL2CHRM5CHKACYP1A2CYP3A4 | |
| SCHEMBL12827301 | 0.76 | LOXL2 (0.42) | LOXL2CHRM5CHKACYP1A2CYP3A4 | |
| SCHEMBL294642 | 0.75 | TSHR (0.64) | CYP3A4CYP2C19ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL733206 | 0.74 | CHRNB2 (0.62) | CHRM5CHKACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3460936 | 0.74 | CHRNB2 (0.71) | CYP1A2CYP2D6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21444971 | 0.74 | LOXL2 (0.50) | LOXL2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7289233 | 0.73 | PYCR1 (0.50) | CYP1A2CYP2C19ALDH1A1HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104763-A1 | NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-06 | — | — | EP | claimed |