Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841191 | 1.00 | ALOX5 (0.49) | ALOX5GPBAR1CYSLTR2CYSLTR1PDGFRB | |
| SCHEMBL7838536 | 0.95 | ALOX5 (0.44) | ALOX5GPBAR1CYSLTR2CYSLTR1PDGFRB | |
| SCHEMBL7838682 | 0.91 | ALOX5 (0.47) | ALOX5GPBAR1CYSLTR2CYSLTR1PDGFRB | |
| SCHEMBL7737535 | 0.89 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL8396421 | 0.88 | GPBAR1 (0.47) | GPBAR1CYSLTR2CYSLTR1MRGPRX4DHFR | |
| SCHEMBL7839312 | 0.87 | PLA2G2D (0.42) | HSD17B10PLA2G2DMRGPRX4RARBCYP3A4 | |
| SCHEMBL7842850 | 0.86 | ALDH1A1 (0.46) | PLA2G2DMRGPRX4CYP3A4 | |
| SCHEMBL8390753 | 0.84 | MRGPRX4 (0.46) | GPBAR1CYSLTR2CYSLTR1NPC1RAB9A | |
| SCHEMBL7830180 | 0.84 | ESR1 (0.41) | PLA2G2DMRGPRX4RARB | |
| SCHEMBL7830297 | 0.84 | RARB (0.47) | NPC1SMN1; SMN2RARBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |