Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145600 | 0.84 | MEN1 (0.48) | CYP3A4SLC6A3MEN1NR1I2KMT2A | |
| SCHEMBL7837943 | 0.82 | SLC6A3 (0.41) | CYP3A4SLC6A3MEN1NR1I2KMT2A | |
| SCHEMBL5566385 | 0.82 | HTT (0.39) | MEN1KMT2AIDO1ALDH1A1KCNH2 | |
| SCHEMBL10672256 | 0.81 | ALDH1A1 (0.46) | CYP3A4MEN1NR1I2KMT2AIDO1 | |
| SCHEMBL7840238 | 0.76 | HSD17B10 (0.53) | CYP3A4SLC6A3MEN1NR1I2KMT2A | |
| SCHEMBL10420876 | 0.74 | ALDH1A1 (0.41) | CYP3A4SLC6A3MEN1NR1I2KMT2A | |
| SCHEMBL9455530 | 0.74 | ALDH1A1 (0.45) | TSHRMEN1NR1I2KMT2AALDH1A1 | |
| SCHEMBL9455449 | 0.73 | CYP19A1 (0.41) | SLC6A3MEN1NR1I2KMT2ASLC6A2 | |
| SCHEMBL11758026 | 0.72 | CYP3A4 (0.39) | CYP3A4TSHRSLC6A3MEN1KMT2A | |
| SCHEMBL10420892 | 0.72 | ALDH1A1 (0.43) | CYP3A4MEN1NR1I2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737672-B1 | Method of producing triazine derivatives | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0737672-A2 | Method of producing triazine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |