Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479217 | 0.89 | HSD17B10 (0.44) | HSD17B10VCAM1ALDH1A1SLC6A3CYP3A4 | |
| SCHEMBL8147067 | 0.87 | MEN1 (0.46) | HSD17B10VCAM1ALDH1A1GPR35MAPT | |
| SCHEMBL11762817 | 0.85 | HSD17B10 (0.57) | HSD17B10VCAM1ALDH1A1SLC6A3CYP3A4 | |
| SCHEMBL10419484 | 0.84 | ALDH1A1 (0.44) | HSD17B10VCAM1ALDH1A1GPR35MAPT | |
| SCHEMBL5561482 | 0.84 | VCAM1 (0.40) | HSD17B10VCAM1ALDH1A1MAPTPDE7A | |
| SCHEMBL10421412 | 0.78 | MEN1 (0.40) | HSD17B10VCAM1ALDH1A1SLC6A3CYP3A4 | |
| SCHEMBL9455474 | 0.77 | MAPT (0.43) | HSD17B10VCAM1ALDH1A1MAPTPDE7A | |
| SCHEMBL7838595 | 0.76 | CYP3A4 (0.45) | ALDH1A1SLC6A3CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL10421676 | 0.76 | ALDH1A1 (0.41) | HSD17B10VCAM1ALDH1A1CYP3A4GPR35 | |
| SCHEMBL11762115 | 0.76 | HSD17B10 (0.46) | HSD17B10VCAM1ALDH1A1SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737672-B1 | Method of producing triazine derivatives | TAKEDA SCHERING PLOUGH ANIMAL (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6211178-B1 | ANTIPROTOZOA AGENTS FOR COCCIDIOIDES; CYCLIZATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| US-5994355-A | ANTIPROTOZOA AGENTS, PARASITICIDE; VETERINARY MEDICINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0737672-A2 | Method of producing triazine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |