Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455474 | 0.80 | MAPT (0.43) | CYP19A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8145600 | 0.74 | MEN1 (0.48) | SLC6A3SMN1; SMN2MEN1NR1I2KMT2A | |
| SCHEMBL2842596 | 0.74 | CFTR (0.57) | CYP19A1KCNA5CFTRSLC6A2SLC6A4 | |
| SCHEMBL7838595 | 0.73 | CYP3A4 (0.45) | KCNH2SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL10672256 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2MEN1NR1I2KMT2AGAA | |
| SCHEMBL6465831 | 0.72 | MAPT (0.46) | SLC6A2SLC6A4SLC6A3SMN1; SMN2MEN1 | |
| SCHEMBL21574585 | 0.70 | KCNA5 (0.45) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL5622301 | 0.70 | MAPK9 (0.51) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1033928 | 0.69 | CYP19A1 (0.49) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8938113 | 0.69 | SMN1; SMN2 (0.53) | CYP19A1KCNA5KCNH2CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196562-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |