Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | CTSG | P08311 | 2/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.31 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452055 | 0.81 | MMP12 (0.34) | ADAPPARGPPARAFAAHPRSS1 | |
| SCHEMBL7451697 | 0.72 | ADA (0.40) | ADAPPARGPPARAFAAH | |
| SCHEMBL7452894 | 0.71 | CNR1 (0.35) | CTSGCTRB1 | |
| SCHEMBL7451266 | 0.71 | HPGD (0.37) | PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL7457016 | 0.70 | ADA (0.39) | ADAFAAH | |
| SCHEMBL6171825 | 0.68 | DHFR (0.41) | MMP2ADRB2ADRB1ADRB3 | |
| SCHEMBL6171832 | 0.68 | DHFR (0.41) | MMP2ADRB2ADRB1ADRB3 | |
| SCHEMBL7456307 | 0.68 | SLC7A5 (0.35) | CTSGCTRB1 | |
| SCHEMBL7449602 | 0.67 | ADRB2 (0.34) | ADAPPARGPPARAPRSS1CTSG | |
| SCHEMBL6171958 | 0.65 | ADA (0.56) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |