Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RECQL | P46063 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449607 | 0.90 | MAPT (0.31) | MAPTNPSR1ALDH1A1RECQLPOLB | |
| SCHEMBL7452899 | 0.82 | CA2 (0.30) | — | |
| SCHEMBL7456315 | 0.78 | SLC7A5 (0.35) | KMT2AMEN1 | |
| SCHEMBL7446159 | 0.70 | RIPK1 (0.37) | — | |
| SCHEMBL7453038 | 0.69 | BCAT2 (0.42) | L3MBTL1ROCK2ROCK1 | |
| SCHEMBL7452060 | 0.67 | MBTD1 (0.33) | MAPTNPSR1ALDH1A1RECQLPOLB | |
| SCHEMBL16263403 | 0.67 | KCNA5 (0.42) | MAPTALDH1A1KMT2AL3MBTL1ATM | |
| SCHEMBL7451270 | 0.67 | ADA (0.38) | ALDH1A1KMT2A | |
| SCHEMBL6525612 | 0.67 | ATM (0.39) | MAPTALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL13871075 | 0.66 | RIPK1 (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |