Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839276 | 0.69 | ALDH1A1 (0.39) | ALDH1A1LMNACDC7DBF4KDM4E | |
| SCHEMBL8946850 | 0.67 | KDM4E (0.62) | ALDH1A1TSHRLMNACDC7DBF4 | |
| SCHEMBL2724098 | 0.66 | LMNA (0.50) | ALDH1A1TDP1LMNAMETAP1FFAR1 | |
| SCHEMBL17479130 | 0.66 | CDC7 (0.49) | ALDH1A1TSHRLMNACDC7DBF4 | |
| SCHEMBL4766667 | 0.66 | JMJD6 (0.58) | ALDH1A1CDC7DBF4KDM4EHPGD | |
| SCHEMBL3224320 | 0.66 | LMNA (0.55) | ALDH1A1TSHRLMNAKDM4EHTT | |
| SCHEMBL12143473 | 0.65 | METAP1 (0.73) | TDP1GRM5METAP1FFAR1METAP2 | |
| SCHEMBL2951237 | 0.65 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1LMNACDC7 | |
| SCHEMBL1561125 | 0.65 | LMNA (0.48) | ALDH1A1TDP1LMNAMETAP1METAP2 | |
| SCHEMBL10375284 | 0.65 | RAB9A (0.62) | ALDH1A1TSHRLMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073642-A1 | THE USE OF DIHYDROPYRIMIDINES AS MEDICAMENTS, AND NOVEL SUBSTANCES | BAYER AG (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054312-A1 | THE USE OF DIHYDROPYRIMIDINES AS MEDICAMENTS, AND NOVEL SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |