Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847053 | 0.83 | RAB9A (0.38) | ALDH1A1KMT2AGAAECE1KDM4E | |
| SCHEMBL17479130 | 0.79 | CDC7 (0.49) | ALDH1A1CDC7DBF4GAAL3MBTL1 | |
| SCHEMBL17064231 | 0.72 | KMT2A (0.40) | ALDH1A1KMT2AGAAECE1HDAC3 | |
| SCHEMBL17874036 | 0.72 | CDC7 (0.46) | ALDH1A1KMT2ACDC7DBF4L3MBTL1 | |
| SCHEMBL7839059 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CDC7DBF4L3MBTL1LMNA | |
| SCHEMBL18074580 | 0.69 | CTSA (0.41) | ALDH1A1KMT2AECE1CTSA | |
| SCHEMBL19259491 | 0.69 | HDAC3 (0.43) | CDC7DBF4ECE1HDAC3HDAC1 | |
| SCHEMBL17479069 | 0.67 | HCRTR1 (0.39) | ALDH1A1KMT2AECE1KDM4ECTSA | |
| SCHEMBL15515454 | 0.67 | CDC7 (0.43) | ALDH1A1CDC7DBF4ECE1HDAC3 | |
| SCHEMBL1565328 | 0.67 | PDPK1 (0.53) | ALDH1A1KMT2AGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073653-A1 | NOVEL 2-HETEROCYCLICALLY SUBSTITUTED DIHYDROPYRIMIDINES | BAYER AG (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054329-A1 | NOVEL 2-HETEROCYCLICALLY SUBSTITUTED DIHYDROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |