Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489526 | 0.84 | ADRB1 (0.49) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL6489528 | 0.84 | ADRB1 (0.49) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL6480809 | 0.81 | CASR (0.45) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL6479255 | 0.81 | ADRB3 (0.56) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL6479253 | 0.81 | ADRB3 (0.56) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL7694546 | 0.77 | ADRB3 (0.56) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL7694548 | 0.77 | ADRB3 (0.56) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL7692661 | 0.76 | MEN1 (0.47) | ADRB1ADRB3CASRADRB2MEN1 | |
| SCHEMBL7687852 | 0.75 | ADRB3 (0.59) | ADRB1ADRB3CASRADRB2KMT2A | |
| SCHEMBL6532071 | 0.75 | ADRB3 (0.59) | ADRB1ADRB3CASRKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140849-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040560-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |