Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489526 | 0.86 | ADRB1 (0.49) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL6489528 | 0.86 | ADRB1 (0.49) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL6479253 | 0.85 | ADRB3 (0.56) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL6479255 | 0.85 | ADRB3 (0.56) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL7839233 | 0.81 | ADRB1 (0.42) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL7692661 | 0.80 | MEN1 (0.47) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL7037442 | 0.79 | CASR (0.52) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL7041984 | 0.79 | ADRB3 (0.59) | CASRADRB3ADRB1CYP2D6ADRB2 | |
| SCHEMBL7687852 | 0.77 | ADRB3 (0.59) | CASRADRB3ADRB1ADRB2KMT2A | |
| SCHEMBL6532071 | 0.77 | ADRB3 (0.59) | CASRADRB3ADRB1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
| EP-1140849-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040560-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | CASR 1910/4885ADRB3 3/4885ADRB1 1/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | CASR 1137/4885ADRB3 3/4885ADRB1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.