Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829756 | 0.91 | SLC10A2 (0.44) | BRD4POLBTUBB4ATUBBTUBA3C | |
| SCHEMBL7822008 | 0.82 | RECQL (0.47) | KMT2APOLBTSHRMAPK1ALDH1A1 | |
| SCHEMBL7836104 | 0.76 | FABP3 (0.44) | KMT2ASMN1; SMN2ALDH1A1NPC1FABP3 | |
| SCHEMBL14917022 | 0.76 | PDE5A (0.48) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9414070 | 0.76 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2MAPK1ALDH1A1NPC1 | |
| SCHEMBL7834035 | 0.75 | ALDH1A1 (0.44) | KMT2APOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL7832560 | 0.75 | TDP1 (0.40) | KMT2ASMN1; SMN2TSHRALDH1A1FABP3 | |
| SCHEMBL8121664 | 0.75 | FABP3 (0.53) | KMT2ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7833827 | 0.75 | ALDH1A1 (0.46) | KMT2APOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL7831401 | 0.75 | SMN1; SMN2 (0.54) | KMT2ASMN1; SMN2ALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |