Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830591 | 0.90 | SLC10A2 (0.47) | RECQLKMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL7834035 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1NPC1KDM4EMAPK1 | |
| SCHEMBL7835953 | 0.83 | ALDH1A1 (0.43) | KMT2AALDH1A1NPC1KDM4EMAPT | |
| SCHEMBL7839707 | 0.82 | BRD4 (0.37) | KMT2AALDH1A1NPC1KDM4EMAPK1 | |
| SCHEMBL7836104 | 0.80 | FABP3 (0.44) | KMT2AALDH1A1NPC1KDM4EMAPT | |
| SCHEMBL14917022 | 0.79 | PDE5A (0.48) | KMT2AALDH1A1NPC1KDM4EMAPT | |
| SCHEMBL9414070 | 0.79 | ALDH1A1 (0.41) | KMT2AALDH1A1NPC1KDM4EMAPK1 | |
| SCHEMBL7813272 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1NPC1KDM4EMAPK1 | |
| SCHEMBL8121664 | 0.78 | FABP3 (0.53) | KMT2AALDH1A1KDM4EMAPTGAA | |
| SCHEMBL7835405 | 0.78 | NPC1 (0.41) | KMT2AALDH1A1NPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567107-B1 | Quinoline and quinazoline derivatives for treating arthritis | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-21 | — | — | EP | claimed |