Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455449 | 0.80 | CYP19A1 (0.41) | KMT2AMEN1SMN1; SMN2CYP19A1 | |
| SCHEMBL8147067 | 0.78 | MEN1 (0.46) | MAPTKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL7840238 | 0.77 | HSD17B10 (0.53) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL10419484 | 0.76 | ALDH1A1 (0.44) | MAPTKMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL9455386 | 0.75 | MAPT (0.57) | MAPTKMT2AHTTLMNAKDM4E | |
| SCHEMBL5561482 | 0.71 | VCAM1 (0.40) | MAPTKMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL10421412 | 0.70 | MEN1 (0.40) | MAPTKMT2AMEN1ALDH1A1VCAM1 | |
| SCHEMBL11765565 | 0.69 | VCAM1 (0.47) | MAPTKMT2AHTTMEN1LMNA | |
| SCHEMBL9455629 | 0.69 | MAPT (0.57) | MAPTKMT2AHTTMEN1SMN1; SMN2 | |
| SCHEMBL2842596 | 0.69 | CFTR (0.57) | SMN1; SMN2KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196562-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| US-4933341-A | Substituted 1,3,5-triazinetriones, for use against parasitic protozoa | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |