Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787997 | 0.82 | PRKCI (0.47) | PRKCIGAAMAPTALDH1A1HTT | |
| SCHEMBL8033091 | 0.82 | PRKCI (0.41) | PRKCICASP1GAAMAPTMAPK1 | |
| SCHEMBL6571085 | 0.81 | CASP1 (0.40) | PRKCICASP1GAAMAPTMAPK1 | |
| SCHEMBL10412397 | 0.80 | PRKCI (0.53) | PRKCIGAAMAPTMAPK1ALDH1A1 | |
| SCHEMBL16543023 | 0.80 | CASP1 (0.42) | PRKCICASP1GAAMAPTMAPK1 | |
| SCHEMBL3790110 | 0.78 | CYP3A4 (0.54) | PRKCICASP1GAAMAPTALDH1A1 | |
| SCHEMBL31621883 | 0.78 | ALDH1A1 (0.54) | PRKCICASP1GAAMAPTALDH1A1 | |
| SCHEMBL3110533 | 0.78 | ALDH1A1 (0.54) | PRKCICASP1GAAMAPTALDH1A1 | |
| SCHEMBL7262816 | 0.78 | TDP1 (0.54) | PRKCIGAAMAPTALDH1A1TDP1 | |
| SCHEMBL6572302 | 0.78 | PRKCI (0.39) | PRKCICASP1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-20250333609-A1 | HYDROPHILIC COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-10-30 | — | — | US | disclosed |
| WO-2025079317-A1 | HYDROPHILIC COMPOSITION | 信越化学工業株式会社 | 2025-04-17 | — | — | WO | disclosed |
| EP-4534598-A1 | HYDROPHILIC COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-04-09 | — | — | EP | disclosed |
| CN-119301194-A | Hydrophilic composition | 信越化学工业株式会社 | 2025-01-10 | — | — | CN | disclosed |
| US-20240368321-A1 | HYDROPHILIC COPOLYMER AND HYDROPHILIC COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| EP-4393964-A1 | HYDROPHILIC COPOLYMER AND HYDROPHILIC COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-07-03 | — | — | EP | disclosed |
| CN-113677680-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117794960-A | Hydrophilic copolymers and hydrophilic compositions | 信越化学工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-117402143-A | EGFR inhibitor and preparation and application thereof | 上海翰森生物医药科技有限公司 | 2024-01-16 | — | — | CN | disclosed |
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |
| US-20120071447-A1 | Antiviral Drugs for Treatment of Arenavirus Infection | SIGA TECHNOLOGIES INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20110172281-A1 | Anti-Viral Drugs for Treatment of Arenavirus Infection | SIGA TECHNOLOGIES INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7977365-B2 | Antiviral drugs for treatment of arenavirus infection | SIGA TECHNOLOGIES, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7872037-B2 | Antiviral drugs for treatment of arenavirus infection | SIGA TECHNOLOGIES, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| US-7674795-B2 | Fluorene derivatives, composition containing said derivatives and the use thereof | AVENTIS PHARMA SA (FR) | 2010-03-09 | — | — | US | disclosed |
| US-20080300265-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVRUS INFECTION | SIGA TECHNOLOGIES INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | AVENTIS PHARMA S.A. (FR) | 2008-06-26 | — | — | US | disclosed |
| US-20070254934-A1 | Antiviral drugs for treatment of arenavirus infection | SIGA TECHNOLOGIES, INC. | 2007-11-01 | — | — | US | disclosed |
| WO-2007106525-A1 | PIPERIDINYL, INDOLYL, PIRINIDYL, MORPHOLINYL AND BENZIMIDAZOLYL UREA DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE FOR THE TREATMENT OF HYPERTENSION, INFLAMMATIONS AND OTHER DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172281-A1 | Anti-Viral Drugs for Treatment of Arenavirus Infection | GK, GALK1, KLK7 | PRKCI 2661/4885CASP1 1364/4885GAA 57/4885 |
| US-20070254934-A1 | Antiviral drugs for treatment of arenavirus infection | GK, GALK1, GZMB | PRKCI 2658/4885CASP1 1241/4885GAA 70/4885 |
| US-20080300265-A1 | ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVRUS INFECTION | GK, MAVS, ZC3HAV1 | PRKCI 2308/4885CASP1 700/4885GAA 29/4885 |
| US-20120071447-A1 | Antiviral Drugs for Treatment of Arenavirus Infection | ZC3HAV1, GZMB, GTF3C3 | PRKCI 2056/4885CASP1 893/4885GAA 49/4885 |
| US-20080153837-A1 | Novel Fluorene Derivatives, Composition Containing Said Derivatives and the Use Thereof | HSP90B1, HSP90AB1, HSP90AA1 | PRKCI 830/4885CASP1 1375/4885GAA 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.