Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 9/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851650 | 0.89 | CHRM5 (0.38) | MAOBPTGESALDH1A1MAPK1TDO2 | |
| SCHEMBL7612058 | 0.86 | BCAT2 (0.42) | MAOBARMAOATLR4TLR2 | |
| SCHEMBL7610613 | 0.83 | MAOB (0.41) | MAOBARMAOATLR4TLR2 | |
| SCHEMBL8087357 | 0.80 | PTGES (0.37) | MAOBARMAOAPTGESMAPK1 | |
| SCHEMBL7615844 | 0.75 | BCAT1 (0.40) | ALDH1A1TDO2 | |
| SCHEMBL7849461 | 0.74 | MAOB (0.48) | MAOBARMAOATLR4TLR2 | |
| SCHEMBL8137593 | 0.74 | CHRM5 (0.41) | MAOBMAOAALDH1A1 | |
| SCHEMBL7618281 | 0.73 | CHRM5 (0.37) | PTGESALDH1A1MAPK1 | |
| SCHEMBL2964633 | 0.71 | MAOB (0.52) | MAOBMAOATLR4TLR2LMNA | |
| SCHEMBL7613555 | 0.71 | CHRM5 (0.37) | PTGESALDH1A1MAPK1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066267-A1 | SUBSTITUTED PHENYL URACILS | Bayer Aktiengesellschaft (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999028302-A1 | SUBSTITUTED PHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-10 | — | — | WO | disclosed |