Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841936 | 0.87 | NHERF1 (0.43) | NHERF1POLBADORA2AADORA1 | |
| SCHEMBL7846556 | 0.85 | LMNA (0.41) | NHERF1POLBHSD17B10GAALMNA | |
| SCHEMBL7841393 | 0.82 | NHERF1 (0.42) | NHERF1POLBHSD17B10LMNAMAPT | |
| SCHEMBL7843694 | 0.76 | GAA (0.46) | POLBGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL7843172 | 0.75 | GABRA1 (0.40) | GAAKDM4EALDH1A1HPGD | |
| SCHEMBL7835904 | 0.75 | GABRA1 (0.40) | — | |
| SCHEMBL7842246 | 0.75 | KDM4E (0.44) | POLBHSD17B10LMNAMAPTKDM4E | |
| SCHEMBL7860741 | 0.74 | GABRA1 (0.39) | POLB | |
| SCHEMBL7834375 | 0.73 | GABRA1 (0.39) | POLBGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL6670139 | 0.73 | CFTR (0.39) | NHERF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |