Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269254 | 0.83 | SLC7A5 (0.56) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7438290 | 0.83 | SLC7A5 (0.56) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5885156 | 0.82 | LTA4H (0.52) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6161681 | 0.82 | SLC7A5 (0.54) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL1126065 | 0.82 | SLC7A5 (0.54) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7277839 | 0.81 | FAAH (0.51) | FAAHLAP3ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL6350217 | 0.81 | LTA4H (0.51) | FAAHLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL17171336 | 0.78 | HPGD (0.64) | FAAHLAP3HPGDCHRM1MMP9 | |
| SCHEMBL7372064 | 0.78 | HPGD (0.64) | FAAHLAP3HPGDCHRM1MMP9 | |
| SCHEMBL6352728 | 0.78 | FAAH (0.46) | FAAHLAP3SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832066-B1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-1996039385-A1 | SUBSTITUTED N-(INDOLE-2-CARBONYL-) AMIDES AND DERIVATIVES AS GLYCOGEN PHOSPHORYLASE INHIBITORS | PFIZER INC. (US) | 1996-12-12 | — | — | WO | disclosed |