Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | LAP3 | P28838 | 5/20 | 0.49 |
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6350217 | 0.99 | LTA4H (0.51) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6359387 | 0.84 | LAP3 (0.54) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL3131492 | 0.84 | LAP3 (0.54) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL5885085 | 0.84 | FAAH (0.46) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL6352728 | 0.84 | FAAH (0.46) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7269254 | 0.83 | SLC7A5 (0.56) | LTA4HLAP3FAAHSLC15A1ALPI | |
| SCHEMBL7438290 | 0.83 | SLC7A5 (0.56) | LTA4HLAP3FAAHSLC15A1ALPI | |
| SCHEMBL7842354 | 0.82 | FAAH (0.47) | LTA4HLAP3ANPEPFAAHSLC15A1 | |
| Hydrochloric Acid SCHEMBL6161681 | 0.82 | SLC7A5 (0.54) | LTA4HLAP3ANPEPRNPEPDNPEP | |
| Hydrochloric Acid SCHEMBL1126065 | 0.82 | SLC7A5 (0.54) | LTA4HLAP3ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992101-B2 | N-(indole-2-carbonyl) and H-thieno[2,3-b]pyrrole-5-carboxamide anti-diabetic agents | PFIZER, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-1562899-A2 | N-(INDOLE-2-CARBONYL)AMIDES AS ANTI-DIABETIC AGENTS | Pfizer Products Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20040157907-A1 | Anti-diabetic agents | PFIZER INC | 2004-08-12 | — | — | US | disclosed |
| WO-2004041780-A2 | N-(INDOLE-2-CARBONYL) AMIDES AS ANTI-DIABETIC AGENTS | PFIZER PRODUCTS INC. (US) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157907-A1 | Anti-diabetic agents | GPR119, INSR, IRS1 | LTA4H 1813/4885LAP3 2259/4885ANPEP 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.