Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088008 | 0.93 | DPP4 (0.36) | HTR1AHTR7DPP4CYP3A4BRD4 | |
| SCHEMBL7853690 | 0.85 | PDE10A (0.36) | HTR1AHTR7DPP4CYP3A4BRD4 | |
| SCHEMBL7852074 | 0.84 | HTT (0.30) | ALDH1A1 | |
| SCHEMBL7837061 | 0.82 | TPH1 (0.30) | ALDH1A1 | |
| SCHEMBL7842857 | 0.80 | GRIN1 (0.39) | ALDH1A1 | |
| SCHEMBL6086514 | 0.80 | PDE10A (0.40) | HTR1AHTR7DPP4CYP3A4BRD4 | |
| SCHEMBL6086282 | 0.78 | DAO (0.45) | KDM4EALDH1A1 | |
| SCHEMBL7855251 | 0.78 | NR3C1 (0.31) | — | |
| SCHEMBL6086685 | 0.78 | HPGD (0.33) | KDM4EALDH1A1 | |
| SCHEMBL6088087 | 0.78 | GRIN1 (0.45) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |