Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086939 | 0.93 | GRIN1 (0.43) | GRIN1GRIN2BTLR7ALDH1A1HPGD | |
| SCHEMBL7837061 | 0.88 | TPH1 (0.30) | ALDH1A1HPGD | |
| SCHEMBL7855251 | 0.84 | NR3C1 (0.31) | — | |
| SCHEMBL7849218 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2BTLR7ALDH1A1HPGD | |
| SCHEMBL6086605 | 0.81 | HPGD (0.42) | TLR7ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7852074 | 0.81 | HTT (0.30) | ALDH1A1 | |
| SCHEMBL7842823 | 0.80 | HTR1A (0.34) | ALDH1A1 | |
| SCHEMBL6086546 | 0.80 | TPH1 (0.34) | GRIN1GRIN2BTLR7ALDH1A1HPGD | |
| SCHEMBL7854092 | 0.79 | ROCK2 (0.32) | — | |
| SCHEMBL6087645 | 0.78 | GRIN1 (0.44) | GRIN1GRIN2BTLR7ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |