Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535696 | 0.87 | L3MBTL1 (0.48) | ACLYL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL5517057 | 0.83 | SLC6A3 (0.59) | SLC6A4SLC6A3ACLYMETAP2L3MBTL1 | |
| SCHEMBL7842884 | 0.82 | L3MBTL1 (0.44) | ACLYL3MBTL1TDP1KDM4EALDH1A1 | |
| SCHEMBL7844565 | 0.77 | SLC6A4 (0.52) | SLC6A4SLC6A3ACLYMETAP2L3MBTL1 | |
| SCHEMBL22290184 | 0.75 | SLC6A4 (0.59) | SLC6A4SLC6A3ACLYMETAP2L3MBTL1 | |
| SCHEMBL30499558 | 0.75 | SLC6A4 (0.59) | SLC6A4SLC6A3ACLYMETAP2L3MBTL1 | |
| SCHEMBL28825335 | 0.75 | KLRK1 (0.52) | METAP2L3MBTL1TLR7 | |
| SCHEMBL3866652 | 0.74 | BRD4 (0.49) | PDE4AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL698991 | 0.74 | L3MBTL1 (0.55) | ACLYL3MBTL1TDP1KDM4EALDH1A1 | |
| Iodide SCHEMBL8735177 | 0.73 | PTGS2 (0.44) | SLC6A4SLC6A3TDP1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |