Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487698 | 0.83 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL5794312 | 0.75 | KDM4E (0.44) | RXFP1CYP1A2KDM4E | |
| SCHEMBL7002652 | 0.74 | KDM4E (0.37) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL1498578 | 0.74 | PLAT (0.41) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL10866870 | 0.74 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL7517643 | 0.73 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL10867176 | 0.73 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL4649996 | 0.72 | GABRA1 (0.56) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL10519192 | 0.72 | CLEC4M (0.53) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 | |
| SCHEMBL8561725 | 0.71 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083920-A1 | NOVEL ANTIBACTERIAL COMPOUNDS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999064051-A1 | NOVEL ANTIBACTERIAL COMPOUNDS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |