Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517643 | 0.89 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL9635290 | 0.86 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL29376920 | 0.86 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL8561725 | 0.85 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL6903795 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL7843262 | 0.83 | RXFP1 (0.40) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL30540821 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL19971590 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL5794312 | 0.82 | KDM4E (0.44) | CYP1A2KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL4765666 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527154-A1 | PROCESS FOR PREPARING 3,4-DIFLUOROANILINE | Pfizer Hospital Products Group, Inc. (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991017138-A1 | PROCESS FOR PREPARING 3,4-DIFLUOROANILINE | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |