Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 4/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 8/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587040 | 0.74 | MKNK1 (0.58) | MKNK1MKNK2MAP2K3KMT2A | |
| SCHEMBL7590161 | 0.74 | ALDH1A1 (0.38) | BAZ2BBAZ2ABRD4BRD2BRD3 | |
| SCHEMBL7954859 | 0.70 | MKNK1 (0.43) | MKNK1MKNK2DHODHP2RX7KDM4E | |
| SCHEMBL15730172 | 0.68 | MKNK2 (0.64) | MKNK1MKNK2MAP4K2DHODHP2RX7 | |
| SCHEMBL29882866 | 0.68 | FNTA (0.48) | BAZ2BBAZ2ABRD4BRD2BRD3 | |
| SCHEMBL28905992 | 0.68 | P2RX7 (0.65) | MKNK1MKNK2P2RX7KDM4EALDH1A1 | |
| SCHEMBL129457 | 0.68 | P2RX7 (0.65) | MKNK1MKNK2P2RX7KDM4EALDH1A1 | |
| SCHEMBL945362 | 0.67 | MKNK1 (0.63) | MKNK1MKNK2DHODHP2RX7 | |
| SCHEMBL15730517 | 0.67 | MKNK1 (0.62) | MKNK1MKNK2DHODHP2RX7ALDH1A1 | |
| SCHEMBL11247100 | 0.67 | MKNK2 (0.48) | MKNK1MKNK2MAP4K2DHODHP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086100-A1 | PYRROLE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064419-A1 | PYRROLE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 1999-12-16 | — | — | WO | disclosed |