Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 13/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.55 |
| ▸ | KIF11 | P52732 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854615 | 0.95 | KIF11 (0.52) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7855327 | 0.92 | KIF11 (0.47) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7855042 | 0.90 | ABCG2 (0.45) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7852589 | 0.89 | ABCG2 (0.55) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7853658 | 0.88 | SIRT1 (0.46) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7847564 | 0.88 | SIRT1 (0.47) | ABCG2ABCB1KIF11SIRT1 | |
| SCHEMBL7677069 | 0.88 | MEN1 (0.49) | ABCG2ABCB1KIF11ALDH1A1SIRT1 | |
| SCHEMBL7851002 | 0.88 | DHODH (0.54) | ABCG2ABCB1KIF11SIRT1 | |
| SCHEMBL7680030 | 0.87 | SIRT1 (0.62) | KIF11SIRT1 | |
| SCHEMBL7853788 | 0.87 | SIRT1 (0.46) | ABCG2ABCB1KIF11SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070716-A1 | Beta-carboline derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-01-24 | — | — | EP | disclosed |