Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846551 | 0.83 | CNR1 (0.52) | KDRALDH1A1MAPK1MEN1LMNA | |
| SCHEMBL7230679 | 0.83 | PPARG (0.37) | GPR119ALDH1A1MAPTLOXLOXL2 | |
| SCHEMBL17560319 | 0.81 | RAB9A (0.48) | ALDH1A1MAPK1MEN1LMNAMAPT | |
| SCHEMBL7843005 | 0.76 | CYP17A1 (0.41) | KDRCYP3A4MEN1MAPTKMT2A | |
| SCHEMBL7841418 | 0.76 | CYP17A1 (0.42) | KDRTDP2MAPTCYP17A1 | |
| SCHEMBL19275814 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2CYP17A1 | |
| SCHEMBL20057655 | 0.75 | CYP17A1 (0.39) | ALDH1A1CYP17A1 | |
| SCHEMBL17569733 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2CYP17A1 | |
| SCHEMBL16355923 | 0.75 | MEN1 (0.44) | ALDH1A1MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL7847281 | 0.75 | KMT2A (0.41) | ALDH1A1MAPK1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157022-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000049015-A1 | PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-24 | — | — | WO | disclosed |