Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446069 | 0.78 | MMP2 (0.55) | MMP2MMP12LMNAKDM4EGABRP | |
| SCHEMBL80450 | 0.78 | CYP2A6 (0.50) | MMP2MMP12LMNAKDM4EGABRP | |
| SCHEMBL1745148 | 0.76 | MMP2 (0.43) | MMP2MMP12LMNAKDM4EGABRP | |
| SCHEMBL5209430 | 0.73 | MAPT (0.44) | LMNAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL728193 | 0.73 | HTT (0.52) | MMP2MMP12LMNAKDM4EGABRP | |
| SCHEMBL13534963 | 0.72 | PRSS1 (0.44) | LMNAKDM4EMAPTNPC1RAB9A | |
| SCHEMBL9672111 | 0.72 | MMP2 (0.50) | MMP2MMP12LMNAKDM4EGABRP | |
| SCHEMBL19021213 | 0.72 | FFAR1 (0.51) | LMNAKDM4ESMN1; SMN2FFAR1FFAR4 | |
| SCHEMBL1145998 | 0.71 | CYP2A6 (0.58) | MAPTRAB9ASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11216527 | 0.71 | FFAR1 (0.49) | MMP2MMP12LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |