Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446069 | 0.82 | MMP2 (0.55) | MMP2MMP12KDM4ELMNAGABRP | |
| SCHEMBL20681670 | 0.79 | ACACB (0.52) | ACACBMAOBAOC3SLC6A4NOS3 | |
| SCHEMBL10300058 | 0.79 | ACACB (0.52) | ACACBMAOBAOC3SLC6A4NOS3 | |
| SCHEMBL7844489 | 0.76 | MMP2 (0.41) | MMP2MMP12ACACBKDM4ELMNA | |
| SCHEMBL728193 | 0.76 | HTT (0.52) | MMP2MMP12ACACBKDM4ELMNA | |
| SCHEMBL27159386 | 0.75 | ACACB (0.44) | ACACBMAOBAOC3SLC6A4NOS3 | |
| SCHEMBL9672111 | 0.75 | MMP2 (0.50) | MMP2MMP12KDM4ELMNAGABRP | |
| SCHEMBL1745009 | 0.75 | ALDH1A1 (0.44) | MMP2MMP12KDM4ELMNAGABRP | |
| SCHEMBL14996347 | 0.74 | APP (0.52) | ACACBKDM4ELMNAMMP3NOS3 | |
| SCHEMBL1746402 | 0.73 | MAOA (0.46) | MMP2MMP12KDM4ELMNAGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031595-B | Photochromic compound and application thereof | 江苏视科新材料股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114031597-B | Polysubstituted dibenzochromene compound and application thereof | 江苏视科新材料股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-114031598-B | Preparation method of polysubstituted dibenzochromene compound | 江苏视科新材料股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114031598-A | Preparation method of polysubstituted dibenzochromene compound | 江苏视科新材料股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031597-A | Polysubstituted dibenzochromene compound and application thereof | 江苏视科新材料股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031595-A | Photochromic compound and application thereof | 江苏视科新材料股份有限公司 | 2022-02-11 | — | — | CN | disclosed |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | VTVX HOLDINGS II LLC | 2021-06-24 | — | — | US | disclosed |
| US-10947180-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2021-03-16 | — | — | US | disclosed |
| US-20200215073-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | HIGH POINT PHARMACEUTICALS, LLC | 2020-07-09 | — | — | US | disclosed |
| US-10471066-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | VTV THERAPEUTICS LLC (US) | 2019-11-12 | — | — | US | disclosed |
| US-20140024645-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2014-01-23 | — | — | US | disclosed |
| US-8551993-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-20130102610-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-8362016-B2 | Phenyl propionic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2386540-A1 | Novel compounds, their preparation and use | High Point Pharmaceuticals, LLC (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110245244-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-10-06 | — | — | US | disclosed |
| US-7943613-B2 | Compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090093484-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | VTVX HOLDINGS II LLC | 2009-04-09 | — | — | US | disclosed |
| EP-1979311-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007071766-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10471066-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | PPARG, PPARA, PPARD | MMP2 3228/4885MMP12 2672/4885ACACB 55/4885 |
| US-20090093484-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | PPARG, PPARD, PPARA | MMP2 3844/4885MMP12 3456/4885ACACB 153/4885 |
| US-10947180-B2 | Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists | PPARG, PPARA, PPARD | MMP2 3228/4885MMP12 2672/4885ACACB 55/4885 |
| US-20110245244-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARG, PPARA, PPARD | MMP2 2566/4885MMP12 2722/4885ACACB 41/4885 |
| US-20200215073-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | MMP2 3228/4885MMP12 2672/4885ACACB 55/4885 |
| US-20130102610-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARG, PPARA, PPARD | MMP2 2566/4885MMP12 2722/4885ACACB 41/4885 |
| US-20210188758-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | MMP2 3228/4885MMP12 2672/4885ACACB 55/4885 |
| US-20140024645-A1 | PHENOXY ACETIC ACIDS AND PHENYL PROPIONIC ACIDS AS PPAR DELTA AGONISTS | PPARG, PPARA, PPARD | MMP2 2042/4885MMP12 1975/4885ACACB 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.