Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325847 | 0.86 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1RAB9A | |
| SCHEMBL5094149 | 0.85 | MAPT (0.55) | MAOBMAPTLMNAKDM4EL3MBTL1 | |
| SCHEMBL27608859 | 0.85 | MAPT (0.55) | MAOBMAPTLMNAKDM4EL3MBTL1 | |
| SCHEMBL17895360 | 0.85 | CA1 (0.58) | MAOACA12CA1CA2CA9 | |
| SCHEMBL3868073 | 0.80 | MAPT (0.63) | MAPTLMNAKDM4EL3MBTL1RAB9A | |
| SCHEMBL28753018 | 0.79 | MAOB (0.58) | MAOAMAOBMAPTLMNAKDM4E | |
| SCHEMBL6321338 | 0.78 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1RAB9A | |
| SCHEMBL6328277 | 0.78 | MAPT (0.64) | MAPTLMNAKDM4EL3MBTL1RAB9A | |
| SCHEMBL6204121 | 0.78 | LMNA (0.64) | MAPTLMNAKDM4EL3MBTL1MAPK1 | |
| SCHEMBL6319805 | 0.78 | MAPT (0.68) | MAOAMAOBMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115716-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018753-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-04-06 | — | — | WO | disclosed |