Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782578 | 0.96 | RAB9A (0.45) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7570657 | 0.89 | RAB9A (0.39) | RAB9AMAPTMEN1POLBKMT2A | |
| SCHEMBL6819174 | 0.84 | MAPT (0.48) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6819179 | 0.84 | MAPT (0.48) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6811367 | 0.84 | SLC6A4 (0.45) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6811369 | 0.84 | SLC6A4 (0.45) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6819076 | 0.81 | CES2 (0.47) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6819080 | 0.81 | CES2 (0.47) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7868304 | 0.81 | CA12 (0.34) | RAB9AMAPTHPGDMEN1POLB | |
| SCHEMBL7868613 | 0.78 | NPFFR2 (0.38) | RAB9AMAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |