Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784385 | 0.90 | NPFFR2 (0.45) | NPFFR2RAB9AKIF11GAAKCNQ3 | |
| SCHEMBL6816713 | 0.81 | KIF11 (0.49) | NPFFR2RAB9AKIF11KCNQ3KCNQ2 | |
| SCHEMBL6816717 | 0.81 | KIF11 (0.49) | NPFFR2RAB9AKIF11KCNQ3KCNQ2 | |
| SCHEMBL6814979 | 0.81 | KMT2A (0.39) | RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL6814976 | 0.81 | KMT2A (0.39) | RAB9AKMT2ASMN1; SMN2MAPT | |
| SCHEMBL7868617 | 0.79 | S1PR1 (0.34) | NPFFR2RAB9AMEN1KMT2A | |
| SCHEMBL7782578 | 0.78 | RAB9A (0.45) | NPFFR2RAB9AMEN1KMT2APOLB | |
| SCHEMBL7844833 | 0.78 | RAB9A (0.42) | NPFFR2RAB9AMEN1KMT2APOLB | |
| SCHEMBL7784388 | 0.77 | NPFFR2 (0.37) | NPFFR2KIF11GAAKCNQ3KCNQ2 | |
| SCHEMBL6816458 | 0.75 | NPFFR2 (0.62) | NPFFR2RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |