Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844950 | 0.88 | KDM4E (0.36) | L3MBTL1KDM4ECA12CA1CA2 | |
| SCHEMBL6792314 | 0.77 | CA12 (0.43) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL7770465 | 0.77 | LMNA (0.35) | L3MBTL1KDM4EPOLBCA12CA1 | |
| SCHEMBL7456709 | 0.77 | KMT2A (0.42) | KDM4EKMT2ANPC1RAB9AHCRTR1 | |
| SCHEMBL7118273 | 0.76 | ACHE (0.43) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL6793677 | 0.75 | KIF11 (0.37) | L3MBTL1POLBTDP1KMT2ANPC1 | |
| SCHEMBL7768682 | 0.75 | HTT (0.40) | KDM4EPOLBTDP1KMT2ANPC1 | |
| SCHEMBL9114805 | 0.74 | KDM4E (0.40) | L3MBTL1KDM4ETDP1CA12CA1 | |
| SCHEMBL8117763 | 0.73 | GRK6 (0.32) | KDM4EPOLBCA12CA1CA2 | |
| SCHEMBL7847009 | 0.73 | CA12 (0.39) | KDM4ECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097155-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002883-A2 | PHOTOCHROMIC SIX-MEMBERED HETEROCYCLIC-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-01-20 | — | — | WO | disclosed |