Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854247 | 0.86 | POLB (0.47) | KMT2AMEN1GAALMNACYP3A4 | |
| SCHEMBL9052805 | 0.82 | GAA (0.35) | KMT2AMEN1GAANPSR1KDM4E | |
| SCHEMBL7856800 | 0.82 | KMT2A (0.40) | KMT2AMEN1GAANPSR1HPGD | |
| SCHEMBL8660070 | 0.80 | KDM4E (0.34) | KMT2AMEN1GAAHPGDKDM4E | |
| SCHEMBL8660073 | 0.79 | KDM4E (0.36) | KMT2AMEN1GAAHPGDKDM4E | |
| SCHEMBL8656765 | 0.79 | GAA (0.31) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| SCHEMBL7852043 | 0.78 | MEN1 (0.35) | KMT2AMEN1GAAHPGDKDM4E | |
| SCHEMBL7855653 | 0.78 | POLB (0.36) | KMT2AMEN1LMNACYP3A4CYP2D6 | |
| SCHEMBL7855481 | 0.77 | MEN1 (0.34) | KMT2AMEN1GAAKDM4EHTT | |
| SCHEMBL7855486 | 0.77 | MEN1 (0.34) | KMT2AMEN1GAAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | claimed |