Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854334 | 0.93 | PTGS1 (0.39) | POLBEGLN1HDAC1HDAC8HDAC6 | |
| SCHEMBL7854244 | 0.92 | MAPT (0.41) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7844774 | 0.92 | PTGS1 (0.38) | POLBEGLN1HDAC1HDAC8HDAC6 | |
| SCHEMBL7844769 | 0.91 | HDAC1 (0.37) | POLBEGLN1HDAC1HDAC8HDAC6 | |
| SCHEMBL7856424 | 0.89 | ALDH1A1 (0.40) | POLBEGLN1HDAC1HDAC8HDAC6 | |
| SCHEMBL7845505 | 0.84 | KDM4E (0.32) | MAPT | |
| SCHEMBL7852293 | 0.84 | KDM4E (0.37) | POLBEGLN1LMNAMAPTMEN1 | |
| SCHEMBL7853643 | 0.84 | KDM4E (0.32) | — | |
| SCHEMBL7852043 | 0.83 | MEN1 (0.35) | EGLN1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL7855481 | 0.82 | MEN1 (0.34) | EGLN1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |