Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852043 | 0.99 | MEN1 (0.35) | MEN1KMT2ALOXL2TSHRHTT | |
| SCHEMBL7855481 | 0.98 | MEN1 (0.34) | MEN1KMT2ALOXL2TSHRHTT | |
| SCHEMBL7852202 | 0.88 | KDM4E (0.31) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7855483 | 0.87 | ALDH1A1 (0.31) | HTTKDM4EALDH1A1GAAGLA | |
| SCHEMBL7854540 | 0.84 | LMNA (0.42) | MEN1KMT2ALOXL2HTTKDM4E | |
| SCHEMBL7845505 | 0.83 | KDM4E (0.32) | LOXL2KDM4EGAAGLA | |
| SCHEMBL7855653 | 0.82 | POLB (0.36) | MEN1KMT2ATSHRALDH1A1EGLN1 | |
| SCHEMBL7854439 | 0.81 | KDM4E (0.33) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7854334 | 0.81 | PTGS1 (0.39) | MEN1KMT2AHTTKDM4EALDH1A1 | |
| SCHEMBL7844608 | 0.81 | KDM4E (0.30) | KDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | claimed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | claimed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | claimed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | claimed |