Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866868 | 0.81 | IDO1 (0.31) | — | |
| SCHEMBL7784388 | 0.79 | NPFFR2 (0.37) | GPR183MEN1NPC1KMT2A | |
| SCHEMBL7868617 | 0.78 | S1PR1 (0.34) | GPR183MEN1NPC1KMT2ASLC6A2 | |
| SCHEMBL7872121 | 0.75 | CES2 (0.42) | — | |
| SCHEMBL7868613 | 0.67 | NPFFR2 (0.38) | MEN1KMT2A | |
| SCHEMBL7860588 | 0.67 | IDO1 (0.36) | MEN1KMT2A | |
| SCHEMBL7872120 | 0.66 | DDR1 (0.36) | NPC1KMT2ASLC6A4 | |
| SCHEMBL7844834 | 0.65 | GCGR (0.33) | SLC6A4 | |
| SCHEMBL7785246 | 0.64 | SLC6A4 (0.34) | NPC1KMT2ASLC6A4 | |
| SCHEMBL7784385 | 0.63 | NPFFR2 (0.45) | MEN1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |