Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 6/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.55 |
| ▸ | CDK1 | P06493 | 5/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.55 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.49 |
| ▸ | RAF1 | P04049 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5558439 | 0.70 | CDK5 (0.41) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3424550 | 0.70 | CDK5 (0.55) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL1250325 | 0.70 | CDK5 (0.73) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL1250329 | 0.70 | CDK5 (0.73) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL6652262 | 0.67 | MAP2K1 (0.44) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL7837428 | 0.66 | MAP2K1 (1.00) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| Aldisin SCHEMBL7844916 | 0.65 | MAP2K1 (1.00) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL3001277 | 0.65 | MAPT (0.52) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL116223 | 0.65 | — | — | |
| SCHEMBL3427648 | 0.63 | TUBB4A (0.68) | MAP2K1RAF1MAPK1PARP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711773-B1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5621099-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0711773-A1 | HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE | SUNTORY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |