Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858074 | 0.86 | NHERF1 (0.54) | NHERF1PYGLPOLBADORA2AADORA1 | |
| SCHEMBL7845733 | 0.76 | PYGL (0.48) | NHERF1PYGLPOLBADORA2AADORA1 | |
| SCHEMBL7848276 | 0.74 | KDM4E (0.46) | PYGLPOLBKDM4EHSD17B10MAPT | |
| SCHEMBL7842334 | 0.74 | NHERF1 (0.58) | NHERF1POLBADORA2AADORA1LMNA | |
| SCHEMBL6670721 | 0.73 | NHERF1 (0.55) | NHERF1POLBADORA2AADORA1LMNA | |
| SCHEMBL6230550 | 0.72 | NHERF1 (0.68) | NHERF1PYGLPOLBADORA2AADORA1 | |
| SCHEMBL7845627 | 0.72 | KDM4E (0.44) | PYGLPOLBLMNAKDM4EHSD17B10 | |
| SCHEMBL7834741 | 0.72 | KDM4E (0.45) | PYGLPOLBKDM4EHSD17B10MAPT | |
| SCHEMBL7834823 | 0.72 | NHERF1 (0.60) | NHERF1POLBADORA2AADORA1MAPT | |
| Hydrochloric Acid SCHEMBL6206076 | 0.72 | NHERF1 (0.67) | NHERF1PYGLPOLBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |