Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848276 | 0.84 | KDM4E (0.46) | PYGLKDM4EHSD17B10POLBMAPT | |
| SCHEMBL7858074 | 0.82 | NHERF1 (0.54) | PYGLKDM4ELMNAHSD17B10NHERF1 | |
| SCHEMBL7834741 | 0.82 | KDM4E (0.45) | PYGLKDM4EHSD17B10POLBMAPT | |
| SCHEMBL7841393 | 0.79 | NHERF1 (0.42) | PYGLKDM4ELMNAHSD17B10NHERF1 | |
| SCHEMBL6670167 | 0.76 | ALDH1A1 (0.49) | KDM4ELMNAHSD17B10POLBMAPT | |
| SCHEMBL7845633 | 0.76 | NHERF1 (0.45) | PYGLKDM4ELMNAHSD17B10NHERF1 | |
| SCHEMBL7848232 | 0.76 | KCNH2 (0.46) | KDM4EHSD17B10POLBMAPT | |
| SCHEMBL7845731 | 0.74 | HSD17B10 (0.44) | PYGLKDM4ELMNAHSD17B10GABRA1 | |
| SCHEMBL6201470 | 0.70 | ADORA2A (0.60) | NHERF1ADORA2AADORA1GABRA1GABRB1 | |
| SCHEMBL7841936 | 0.69 | NHERF1 (0.43) | NHERF1ADORA2AADORA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |