Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 10/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847258 | 0.89 | ALDH1A1 (0.34) | DDR1GRIN1GRIN2BMAPTKDM4E | |
| SCHEMBL7844403 | 0.86 | GRIN1 (0.37) | GRIN1GRIN2BMAPTKDM4E | |
| SCHEMBL7837064 | 0.84 | HSD17B10 (0.39) | GRIN1GRIN2BMAPTKDM4EHTT | |
| SCHEMBL7847762 | 0.84 | TYMS (0.38) | DDR1MAPTKDM4E | |
| SCHEMBL7847016 | 0.83 | TYMS (0.46) | DDR1MAPTKDM4ETSHR | |
| SCHEMBL8189652 | 0.83 | KDM4E (0.45) | MAPTKDM4EHTTSMN1; SMN2TSHR | |
| SCHEMBL6087627 | 0.83 | TSHR (0.34) | DDR1MAOBGRIN1GRIN2BMAPT | |
| SCHEMBL7836586 | 0.79 | HSD17B10 (0.51) | GRIN1GRIN2BMAPTKDM4ETSHR | |
| SCHEMBL7847304 | 0.78 | GRIN1 (0.44) | GRIN1GRIN2BCYP2D6 | |
| SCHEMBL7836051 | 0.76 | MEN1 (0.33) | GRIN1GRIN2BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |