Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847258 | 0.92 | ALDH1A1 (0.34) | DDR1KDM4EALDH1A1P2RX3HSD17B10 | |
| SCHEMBL7844403 | 0.86 | GRIN1 (0.37) | KDM4EALDH1A1P2RX3HSD17B10MEN1 | |
| SCHEMBL7837064 | 0.86 | HSD17B10 (0.39) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL8189652 | 0.86 | KDM4E (0.45) | TYMSKDM4EALDH1A1P2RX3MEN1 | |
| SCHEMBL7845923 | 0.84 | DDR1 (0.35) | DDR1KDM4EMAPT | |
| SCHEMBL6086132 | 0.82 | TYMS (0.38) | TYMSKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL7836586 | 0.81 | HSD17B10 (0.51) | KDM4EALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL7847304 | 0.81 | GRIN1 (0.44) | MEN1KMT2A | |
| SCHEMBL7847016 | 0.80 | TYMS (0.46) | TYMSDDR1KDM4EALDH1A1P2RX3 | |
| SCHEMBL7847089 | 0.79 | POLB (0.33) | DDR1KDM4EALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |