Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847258 | 0.91 | ALDH1A1 (0.34) | KDM4EALDH1A1P2RX3HPGDSMN1; SMN2 | |
| SCHEMBL7836586 | 0.88 | HSD17B10 (0.51) | KDM4EALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL7847304 | 0.87 | GRIN1 (0.44) | CYP3A4MEN1KMT2A | |
| SCHEMBL7837064 | 0.86 | HSD17B10 (0.39) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7847762 | 0.86 | TYMS (0.38) | KDM4EALDH1A1P2RX3MEN1KMT2A | |
| SCHEMBL7844403 | 0.86 | GRIN1 (0.37) | KDM4EALDH1A1P2RX3MEN1KMT2A | |
| SCHEMBL7847016 | 0.86 | TYMS (0.46) | KDM4EALDH1A1P2RX3MEN1KMT2A | |
| SCHEMBL7845923 | 0.83 | DDR1 (0.35) | KDM4ESMN1; SMN2MAPTTSHRHTT | |
| SCHEMBL7849134 | 0.83 | LMNA (0.40) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7848747 | 0.83 | GRIN1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061563-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |