Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847258 | 0.92 | ALDH1A1 (0.34) | HSD17B10KDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL7836586 | 0.90 | HSD17B10 (0.51) | HSD17B10KDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL7847762 | 0.86 | TYMS (0.38) | HSD17B10KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7844403 | 0.86 | GRIN1 (0.37) | HSD17B10KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8189652 | 0.86 | KDM4E (0.45) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL7845923 | 0.84 | DDR1 (0.35) | KDM4EMAPTGRIN1GRIN2BTSHR | |
| SCHEMBL7848233 | 0.83 | MTNR1A (0.39) | HSD17B10KDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL6085479 | 0.82 | MTNR1A (0.37) | HSD17B10KDM4EMTNR1AMTNR1BMEN1 | |
| SCHEMBL7847304 | 0.81 | GRIN1 (0.44) | MEN1KMT2AGRIN1GRIN2B | |
| SCHEMBL7843309 | 0.80 | HSD17B10 (0.38) | HSD17B10KDM4EMTNR1AMTNR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |