SCHEMBL6545475

SCHEMBL6545475

O=c1nc(-c2ccccc2Cl)c2c(=O)nc(-c3ccccc3Cl)c1=2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
GLA P06280 1/20 0.44
MAOB P27338 1/20 0.44
CYP2A6 P11509 1/20 0.43
KMT2A Q03164 2/20 0.42
GUSB P08236 1/20 0.42
C1R P00736 1/20 0.42
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NOTUM Q6P988 2/20 0.42
DCUN1D1 Q96GG9 2/20 0.42
PTPRC P08575 1/20 0.41
ELANE P08246 1/20 0.41
DPP4 P27487 1/20 0.41
MEN1 O00255 1/20 0.41
CNR1 P21554 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8119337 0.83 SCN9A (0.50) KMT2ANOTUMMEN1
SCHEMBL10481215 0.77 MAPK1 (0.41) KDM4EALDH1A1MAOBKMT2AC1R
SCHEMBL1728362 0.76 KDM4E (0.37) KDM4EALDH1A1GLAMAOBCYP2A6
SCHEMBL5451049 0.75 ALOX15 (0.44) KDM4EALDH1A1GLAMAOBCYP2A6
SCHEMBL6480259 0.75 POLB (0.47) KDM4EALDH1A1CYP2A6KMT2ANPC1
SCHEMBL7798696 0.72 TRPA1 (0.39) ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL7846078 0.71 KDM4E (0.50) KDM4EALDH1A1GLAKMT2AGUSB
SCHEMBL6479992 0.71 PAX8 (0.52) ALDH1A1CYP2A6KMT2ANPC1TP53
SCHEMBL771038 0.70 KDM4E (0.46) KDM4EALDH1A1GLAKMT2ANPC1
SCHEMBL1720312 0.69 PAX8 (0.45) ALDH1A1CYP2A6KMT2ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1230094-B1 METHOD FOR APPLYING COLOURED CHARACTERS ON A DATA STORAGE MEDIUM WHICH IS PREFERABLY MADE FROM PLASTIC AND DATA STORAGE MEDIA ACCORDING TO SAID METHOD ORGA KARTENSYSTEME GMBH (DE) 2004-01-14 EP disclosed