SCHEMBL7846432

SCHEMBL7846432

Cc1ccccc1CN1CCc2ccc(S(=O)(=O)CCCC3CCN(C(=O)OC(C)(C)C)CC3)cc2CC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.51
TGFBR1 P36897 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7837991 0.86 GPR119 (0.59) GPR119
SCHEMBL7855571 0.84 GPR119 (0.52) GPR119TGFBR1
SCHEMBL7853078 0.84 ACHE (0.46)
SCHEMBL7857235 0.83 GPR119 (0.53) GPR119TGFBR1
SCHEMBL7847165 0.83 LMNA (0.44)
Hydrochloric Acid SCHEMBL7849367 0.82 CXCR4 (0.49)
SCHEMBL7838209 0.82 GPR119 (0.55) GPR119
SCHEMBL7847863 0.81 GPR119 (0.55) GPR119
Hydrochloric Acid SCHEMBL7847684 0.79 ALDH1A1 (0.43)
SCHEMBL27137179 0.77 GPR119 (0.62) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122252-A1 NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME Takeda Chemical Industries, Ltd. (JP) 2001-08-08 EP disclosed